Value Genome LLC
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Real-World Analysis: Beta-Thalassemia Patient Complications

The Client

The Challenge

The Challenge

  • Industry: Healthcare 
  • Goal: Understand the clinical and economic burden of beta-thalassemia

The Challenge

The Challenge

The Challenge

  • Limited Data: The client needed real-world data on beta-thalassemia patients to inform their decision-making

The Solution

The Solution

The Solution

  • Retrospective Claims Study: Conducted a detailed analysis of Taiwan's National Health Insurance Research Database from 2001 to 2016.

Key Findings

The Solution

The Solution

  • Higher red blood cell transfusion (RBCT) burden was generally associated with a significantly higher prevalence of complications among patients with beta-thalassemia ​
  • Patients receiving higher numbers of RBCT units have a significantly increased burden of cardiac, endocrine, liver and renal complications

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